KMID : 0806120120420020207
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´ëÇÑ°£È£ÇÐȸÁö 2012 Volume.42 No. 2 p.207 ~ p.216
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Depression and Risk Factors in Patients with Crohn¡¯s Disease
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Cho Ok-Hee
Yoo Yang-Sook Yang Suk-Kyun
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Abstract
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Purpose: This study was conducted to determine the risk factors among patients with depression with Crohn¡¯s disease.
Methods: Data were collected by questionnaire from 276 patients who were diagnosed with Crohn¡¯s disease at a tertiary hospital located in Seoul. Measurements included patients¡¯ demographic characteristics, clinical characteristics, depression level, and health-related quality of life. Data were analyzed using t-test, ¥ö2-test, Wilcoxon rank sum test, and logistic regression analyses.
Results: The incidence rate of depression (BDI-II¡Ã14scores) was 31.9% (n=88). Univariate analysis revealed that being a woman, school graduation status, economic status (low), BMI(<18.5Kg/m2), disease duration (¡Ã3 years), CDAI (¡Ã150 scores), frequency of hospital admission (¡Ã2), extra-intestinal manifestation (arthralgia, stomatitis), administration of 5-aminosalicylic acid, and disease related quality of life (SIBDQ<50 scores) were associated with depression. Multivariate analysis revealed that economic status (low), school graduation status, and quality of life (SIBDQ<50 scores) were more likely to report high level of depression.
Conclusion: Future research should consider managing depression as an essential component of comprehensive care for patients with Crohn¡¯s disease. In addition, further research is needed to develop strategies to better improve quality of life among patients with Crohn¡¯s disease who are depressed.
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KEYWORD
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Crohn¡¯s disease, Depression, Risk factors
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